The caffeine present in many ergotamine-containing combinations helps ergotamine work better and faster by causing more of it to be quickly absorbed into the body. The therapeutic efficacy of Calcitriol can be decreased when used in combination with Dexamethasone. The risk or severity of adverse effects can be increased when Rizatriptan is combined with Pipotiazine. After 84 days of treatment, all nebivolol groups had significantly higher percentages of patients who responded to therapy (i. For this reason, oral administration is recommended either 1 h before or 1 h after meals. Antimuscarinic drugs for bladder problems with a possible risk for QT prolongation and TdP that should be used cautiously and with close monitoring with donepezil include solifenacin and tolterodine.
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